Enhance.MD

Provider Profile Name: Enhance.MD
Website: enhance.md
Legal Structure: Enhance.MD LLC (patient management platform); clinical services delivered by Enhance Wellness PC and iThriveMD PC
Provider Type: Telehealth — Virtual Only, Direct-to-Consumer

Operating Details

• Licensed to operate in all 50 states; weight loss medications currently available in 40 states and Washington D.C.
• Fully virtual — online intake, lab work at Quest Diagnostics, video consultation with licensed provider
• No separate membership fee — list prices include medication, provider visits, lab testing, supplies, and coaching
• LegitScript certified
• Flat pricing at all doses — price does not increase as dosage titrates upward
• Cancel anytime without penalty before medication has shipped
• 100% money-back guarantee if found ineligible after completing the intake process
• No insurance accepted

Approach Enhance.MD offers a physician-led weight management and wellness program focused on sustainable results and long-term health, combining GLP-1 medications, peptides, and NAD+ therapies with medical oversight and ongoing support to help regulate appetite, improve metabolic health, and support overall well-being.

About the Company

Enhance.MD LLC is a patient management platform that provides administrative and operational support to physicians and practitioners employed by Enhance Wellness PC and iThriveMD PC, who deliver care through a telehealth platform. Enhance.MD LLC does not provide medical or pharmacy services, employ healthcare providers, or influence clinical decision-making. This three-entity structure — platform, management company, and independent medical practice — is the standard model used across the direct-to-consumer compounded GLP-1 space.

What meaningfully differentiates Enhance.MD from most platforms in this series is its mandatory lab work requirement. New patients must complete a comprehensive blood test at a Quest Diagnostics facility before their consultation, with metabolic lab testing repeated every six months thereafter. Most compounded GLP-1 platforms reviewed here do not require baseline labs, offering optional or skippable testing instead. Enhance.MD’s lab-first model reflects a more clinically thorough intake process, though it adds 3–5 business days to the onboarding timeline and requires patients to physically visit a Quest location.

The platform is also LegitScript certified, which means it has met strict standards for quality, transparency, and legal compliance — with LegitScript auditing provider credentials, data security, and prescription practices.

GLP-1 Weight Loss

• Lose pounds of fat every week
• Money Back Guarantee
• No membership or hidden fees! Everything you need is included
• Start for just $179, no insurance required + free shipping

GLP-1 for Just $179

100k MembersHSA/FSA ApprovedFrom $179

GLP-1 Offerings and Weight Loss Services

Enhance.MD structures its GLP-1 offerings across three tiers — Core, Advanced, and Elite — plus a microdosing option:

GLP-1 Core:

• Compounded Semaglutide (injectable) — weekly injection; single GLP-1 receptor agonist; all doses covered at one price

GLP-1 Advanced:

• Compounded Tirzepatide (injectable) — weekly dual GLP-1/GIP receptor agonist; ongoing provider care, metabolic labs every 6 months, supplies, wellness coaching, and full platform access included

GLP-1 Elite:

• A combination semaglutide + tirzepatide formulation. This option should be approached with caution: the Elite program combines semaglutide and tirzepatide into one treatment, but according to the American Diabetes Association, compounded mixes like this come with real concerns, including inconsistent dosing, questionable purity, and no established standards for safety or quality.

Microdosing Tirzepatide:

• Lower-dose tirzepatide starting at $169/month for 1mg/week

Included in all plans: All plans include four weeks of medication, provider consultations, metabolic lab testing every six months, syringes, alcohol pads, and nutrition and wellness coaching — with no additional fees.

Eligibility: The minimum BMI for new patients is 25.

Pricing by Type — and What Reviewers Say

Enhance.MD’s flat-dose pricing is one of its primary differentiators — the price for any medication is the price you’ll pay every time, regardless of dosage.

Published Monthly Pricing:

• GLP-1 Core (Semaglutide): Starting at $112 first month, then $212/month (all doses)
• Microdosing Tirzepatide: Starting at $169/month (1mg/week)
• GLP-1 Advanced (Tirzepatide): Starting at $180 first month, then $280/month (all doses)
• Monthly tirzepatide: $379/month; annual subscription: $3,866 ($322/month)
• Monthly semaglutide: $249/month; annual subscription: $2,540 ($212/month)
• Discounts also available for quarterly and semiannual upfront payments

What reviewers say about pricing: One long-term tirzepatide user described paying $323/month for 2.5mg tirzepatide with no extra fees and no adverse reactions over nearly two years, calling it a clear improvement over previous providers that charged additional monthly fees on top of medication costs. Another reviewer specifically cited the flat-dose pricing as a core value, saying it is “critical for the long-term care of patients.”

Reviews from Trustpilot and Google

Enhance.MD has 147 reviews on Trustpilot at the time of writing. The overall tone skews positive, with the majority of reviews rating five stars, but a meaningful minority of one-star reviews raises specific operational concerns worth flagging.

What patients praise:

• Easy and efficient onboarding, friendly and knowledgeable staff, and quick medication delivery are the most consistent positives across recent reviews
• Provider-patient continuity is cited as a standout feature — reviewers describe being able to choose their doctor within their state and maintain the same provider across monthly appointments
• The mandatory lab work requirement is viewed positively by patients who value clinical rigor, with one reviewer specifically praising that it felt like working with “real medical professionals” compared to competitors who skip labs
• Multiple reviewers cite significant results — 30 lbs in one year, 45 lbs in six months, and 57 lbs in under two years

Common complaints:

• Shipping delays are the most frequent complaint — Enhance.MD acknowledges average onboarding timelines of 10–15 business days from subscription start to medication receipt, which some patients describe as unacceptably long
• Warm medication arrival during transit is a recurring concern, with reviewers noting FedEx delays leaving packages in transit for 5+ days. Enhance.MD’s official response states its pharmacy partners certify semaglutide as stable up to 105°F during transit for 5 days — a position that has drawn skepticism from some reviewers
• Pharmacy switching has caused treatment gaps for some patients — one reviewer, an RN, reported that after a pharmacy change she experienced no weight loss or medication effects for months and suspected the vials contained sterile water rather than active compound, submitting a sample for independent lab testing before canceling
• Some reviewers report receiving less medication than expected in vials, without a clear explanation from customer service

Compounding Pharmacies Used

Most Enhance.MD prescriptions are filled at 503A compounding pharmacies. Named pharmacy partners identified across reviews and independent sources include Rite-Away Pharmacy, Vios Compounding Pharmacy, and TruMedsRx, with Hallandale Pharmacy and Strive Pharmacy used historically during earlier periods.

Rite-Away Pharmacy is one of Enhance.MD’s trusted compounding partners, preparing GLP-1 compounds tailored to each prescription. Vios Compounding Pharmacy is known for fast turnaround times and a broad range of specialized solutions, customizing doses from base ingredients. TruMedsRx is a mail-order compounding pharmacy based in Fairfax, Virginia, licensed in 48 states, serving over 85,000 patients.

The pharmacy switching history documented in Trustpilot reviews is worth noting — multiple patients describe receiving shipments from different pharmacies at different points in their treatment, with some reporting inconsistent potency or efficacy after transitions. Enhance.MD attributes past switches to pharmacy availability and regulatory requirements during the post-shortage period, which is a plausible operational explanation, but the pattern warrants patient awareness before enrolling.

Note: Enhance.MD’s “Elite” combined semaglutide + tirzepatide program has been flagged by the American Diabetes Association for lacking established safety and quality standards — patients should discuss this option carefully with their provider before choosing it over standard single-compound protocols. Onboarding requires a Quest Diagnostics lab visit before consultation, adding approximately one week to the start timeline. Pricing reflects published and independently reported rates as of early 2026 and is subject to change; the $112/$180 first-month figures reflect promotional introductory pricing. Compounded medications are not FDA-approved. Weight loss medications available in 40 states and DC only — verify state availability at enhance.md before enrolling. Always consult a licensed medical provider before beginning any GLP-1 program.