Updated: July 3, 2026

MDLifespan

MDLifespan is a physician-led longevity and detoxification clinic headquartered in Chicago, Illinois, specializing in therapeutic plasma exchange (TPE) through its patent-pending PlasmaXchange protocol, alongside biomarker testing, IV nutrient therapy, and regenerative treatments.
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Clinic Profile

MDLifespan has its main clinic at 2400 N Ashland Avenue, Suite 250, Chicago, Illinois. As the leader of modern medicine, MDLifespan is known as the very first physician-owned organization in the country that is exclusively focused on therapeutic plasma exchange for longevity and regenerative detoxification. Being a Public Benefit Corporation, MDLifespan combines the best medical practices with a concern about general health optimization. To provide patients who do not reside in Chicago with an opportunity to receive proper consultations, MDLifespan provides nationwide telemedicine services enabling clients to develop their treatment plans online and then come to the clinic in Chicago for special procedures.

The clinic does not participate with insurance companies; services are offered on a self-pay basis through individual procedures or fully customized programs.

  • Address: 2400 N Ashland Avenue, Suite 250, Chicago, IL 60614
  • Phone Number: (844) 752-7629
  • Website: mdlifespan.com
  • Insurance: Not Accepted (Self-Pay Only)

Background and History

MDLifespan was launched in 2022 by Dr. Paul Savage, a physician with vast experience, after setting up the company during the period when he took retirement. Having sold his own profitable practice on age management and moving to Brazil, the enthusiasm for restorative medicine was rejuvenated in Dr. Savage due to the findings from an intensive double blind placebo control experiment on the benefits of plasma exchange therapy in slowing down cellular aging. The concept that the best health is determined by how much cellular waste one eliminates rather than what they inject in their body drove him to launch MDLifespan.

The core of the process lies in the use of the unique PlasmaXchange protocol that Dr. Savage defines metaphorically as “an oil change for humans.” The method builds on the basis of the established medical procedure of therapeutic plasma exchange (TPE), a proven treatment method employed in hospitals for more than five decades now, and implements it to promote a proactive detoxification and overall wellness of the patient.

During 2023 and 2024, the facility conducted more than 300 TPEs combined with specific intravenous nutritional therapies, as well as daily supplement powders and regenerative therapy. Presently, the company is developing its network around the country, starting from the advanced facilities in Chicago.

Services and Programs

MDLifespan organizes its clinical services and programs based on the PlasmaXchange protocol, offering services using innovative diagnostic tools and layered regenerative therapies.

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Therapeutic Plasma Exchange (PlasmaXchange Protocol)

Using specialized hospital-grade therapeutic plasma exchange systems, MDLifespan filters the patient’s blood, removing plasma and replacing it to cleanse the body of harmful substances such as toxins, heavy metals, and inflammatory biomarkers. Such therapies are classified into the following targeted protocols:

  • MDL Brain: A special protocol for improving brain health.
  • MDL Heart: A therapy that is intended to reduce vascular inflammation and improve cardiovascular function.
  • MDL Immunity: Structural support to boost immune system strength.
  • MDL Longevity: The main anti-aging protocol centered on cellular rejuvenation.
  • MDL Toxin: A detoxifying program to cleanse the body of harmful environmental contaminants and heavy metals.
  • MDL Baby: An unusual detox program to prepare parents’ bodies for conception.
  • MDL Cancer: A protocol specially targeting systemic inflammation and improvement of metabolic health.

Diagnostics and Testing

  • In order to provide accuracy, the clinic employs tests that include a panel of diagnostic testing of deep-dive biomarkers and environmental exposures. This involves specialized testing for aging cells, cancer biomarkers, heart risks, hormones, immunity, gut microbiota, systemic toxins, neurotransmitters, and microplastics load.

Supportive and Regenerative Therapies

  • As part of the filtration process, patients will receive custom IV nutrient formulas, an exclusive daily powder supplement designed to support cell vitality in between visits, as well as regenerative treatments in conjunction with virtual/real-time doctor consultations.

Doctors and Medical Professionals

Chicago headquarters operates through a team of doctors, specialists, and wellness coaches, making sure that detoxification is integrated into the life of the patient.

Dr. Paul Savage (Founder, CEO, and Chief Medical Officer): As the creator of the PlasmaXchange protocol, Dr. Savage offers more than 35 years of medical expertise to the clinic. Dr. Paul graduated from the University of Michigan Medical School with a degree in Medicine and completed his training for emergency physicians in the Detroit Medical Center. Dr. Paul has earned a Fellowship in Metabolic Medicine from George Washington University and a Fellowship in Stem Cell Therapy from the University of South Florida, along with a bachelor’s degree in mathematics from Michigan State University. His certifications include FACEP and FAARM and formerly the Founder of BodyLogicMD, a chain of bioidentical hormone clinics throughout the country.

Dr. Moises Irizarry-Roman: An expert physician specializing in sports medicine and autologous stem cell therapies.

Dr. Peter Schulz: Licensed chiropractor and clinical medical consultant to help with alignment and neuromuscular functions.

Dr. Nikol Hopkins: Naprapathic doctor, clinical nutritionist, and metabolism-based weight loss expert.

Dr. Gertrude Lyons: Passionate life coach helping individuals with behavioral and emotional integration as well as goal setting.

Joey Thurman: Virtual personal fitness trainer helping develop fitness routines for people all across America.

Reviews and Patient Feedback

Since MDLifespan is a rather new establishment, opened in 2022, the available information in terms of public reviews is scarce in relation to the clinic as an independent organization. At the same time, Dr. Paul Savage has a rather detailed clinical experience that spans several decades. The patient reviews for Dr. Savage on independent medical websites such as Healthgrades are diverse in their nature and indicate an average score of approximately 3.3 out of 5 stars in terms of recommendation.

While many patients appreciate his innovations and knowledge about longevity medicine, some reviews provide a critical outlook on the expectations from the clinical treatment. It is advised that potential patients review the existing scores and contact the clinic personnel to learn more about the approach to patient-oriented treatment.

Testimonials and Quotes

No verifiable patient testimonials specific to the MDLifespan clinic were publicly available at time of writing. Prospective patients can request current patient outcomes and references directly from the clinic.

Pricing and Value Signals

MDLifespan does not participate with insurance; all services are self-pay. The clinic offers both individual procedures and fully customized longevity programs, and provides free physician consultations for patients and practitioners interested in evaluating their toxic burden and identifying an appropriate protocol. Specific procedure pricing is provided directly by the clinic during consultation.

Verification Notes

  • Address: 2400 N Ashland Avenue, Suite 250, Chicago, IL 60614 verified via MDLifespan locations and Chicago location pages.
  • Phone: (844) 752-7629 verified via the official Chicago location page.
  • Verified providers: Dr. Paul Savage, Dr. Moises Irizarry-Roman, Dr. Peter Schulz, Dr. Nikol Hopkins, Dr. Gertrude Lyons, and Joey Thurman.
  • Education, board certification, and fellowships of Dr. Paul Savage verified via the official leadership profile.
  • Founded in 2022 as a Public Benefit Corporation (PBC); “oil change for humans” positioning and 300+ Therapeutic Plasma Exchange (TPE) procedures (2023-2024) verified.
  • Self-pay only; no insurance verified via FindaTopDoc page of Dr. Paul Savage.
  • Healthgrades reports approximate likelihood-to-recommend score of 3.3/5 and mixed patient reviews.
  • PlasmaXchange protocols and diagnostic testing services verified via the official website.
  • Hours: Not publicly available; contact the clinic directly.
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MDLifespan Contacts

  • 770 N Halsted St Ste 204, Chicago, IL 60642, United States

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