Kentuckiana Integrative Medicine

Clinic Profile

Kentuckiana Integrative Medicine (regenmedky.com) is a physician-led integrative medicine practice serving the Louisville, KY and Southern Indiana region from a small, friendly, personalized office in Jeffersonville, Indiana. The clinic specializes in regenerative and functional medicine that aims to restore overall health, energy, and strength, and welcomes new patients of all ages. Its team brings over 24 years of medical experience from Dr. Cruz and more than 70 combined years of provider experience.

Address: 405 E Court Ave, Suite 102, Jeffersonville, IN 47130 Phone: (812) 913-4416 Hours: Monday, Wednesday, Friday 7:30 a.m.–5:00 p.m.; Tuesday & Thursday 7:30 a.m.–6:00 p.m.; Saturday & Sunday closed Website: regenmedky.com

Background and History

Kentuckiana Integrative Medicine is the private practice of Dr. Rafael F. Cruz, MD, a physician whose journey into integrative medicine began during his anesthesia and pain-clinic training, where he saw the limits of conventional interventions and began exploring regenerative approaches such as prolotherapy. After years practicing emergency medicine and seeing many preventable conditions, his focus shifted toward disease prevention and integrative, regenerative therapies.

Today the practice blends the best of conventional and natural/integrative medicine, organized into several divisions — regenerative medicine, integrative medicine, a Ketamine Institute, and weight loss and wellness programs. The clinic emphasizes root-cause care and a “paying it forward” philosophy, providing significant free and discounted patient care and charitable contributions each year.

Services and Programs

Kentuckiana Integrative Medicine offers a broad menu across weight loss, regenerative medicine, and wellness.

Medical Weight Loss

• Medically supervised weight loss programs
• Prescription medications including Phentermine, HCG, and Semaglutide
• Lipotropic injections
• Pharmaceutical-grade nutritional supplements
• Healthy eating lifestyle program and coaching

Regenerative Medicine

• Non-surgical treatment for musculoskeletal pain, arthritis, and injury
• Hyaluronic gel joint injections with fluoroscopic X-ray guidance
• Amniotic tissue wound covers for non-healing/diabetic wounds

Integrative & IV Therapies

• IV vitamin therapy (immune support, fatigue, infections, and more)
• Ozone therapy and oxidative therapies
• Integrative support for heart disease, chronic fatigue, and autoimmune conditions

Ketamine Therapy

• IV ketamine therapy (a VA-approved treatment center) for treatment-resistant depression, PTSD, OCD, bipolar, migraines, CRPS, pain, and addiction/medication reduction

Additional

• Urgent care and telemedicine

Doctors and Medical Professionals

Kentuckiana Integrative Medicine is led by its founding physician, supported by nurses and clinical staff.

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Dr. Rafael F. Cruz, MD, CIME — Founder & Medical Director

Dr. Cruz is board-certified by the American Board of Emergency Medicine (1997–2017) and a Certified Independent Medical Examiner (CIME). He built Kentuckiana Integrative Medicine around blending conventional and integrative/natural medicine, developing expertise in regenerative therapies (prolotherapy, joint injections, regenerative cell therapies), oxidative therapies (ozone, ultraviolet blood irradiation), ketamine therapy, and medically supervised weight loss. His weight loss approach focuses on overall well-being and finding the underlying cause of weight gain rather than appearance alone, supported by pharmaceutical-grade Pure Encapsulations supplements. He brings over 24 years of medical experience to the practice.

Clinical & Support Team

Dr. Cruz is supported by a team of doctors, nurses, and staff with more than 70 combined years of experience as medical providers. Team members are recognized by name in patient reviews (including Richell). Prospective patients can confirm the current provider roster and credentials directly with the clinic.

Reviews and Patient Feedback

Kentuckiana Integrative Medicine maintains review profiles across Google, Yelp, and Facebook (where its page has 471+ likes), with patients highlighting positive experiences with Dr. Cruz and the team. The practice reports that about 90% of its weight loss patients reach and maintain their goal weight, with many also improving blood pressure, Type 2 diabetes, and cholesterol. Prospective patients are encouraged to check current ratings on Google and Yelp for the latest feedback.

Testimonials and Quotes

The following testimonial is drawn from the practice’s Yelp presence:

“Great experience with Dr. Cruz and Richell and the team at Kentuckiana Integrative Medicine.” — Yelp reviewer

Additional patient success stories are featured across the practice’s website divisions; prospective patients can view current testimonials on the clinic’s website and Google profile.

Pricing and Value Signals

Most therapies at Kentuckiana Integrative Medicine are self-pay, as many integrative and regenerative treatments are not covered by insurance (consultation fees are noted as approximately $300, or $400 for neurological consults). The clinic emphasizes safe, affordable, long-standing weight loss programs and offers free discovery calls. It also provides significant free and discounted patient care as part of its “pay it forward” philosophy. Specific treatment pricing is provided during consultation.

Verification Notes

• Address (405 E Court Ave, Suite 102, Jeffersonville, IN 47130), phone (812) 913-4416, and hours confirmed from Yelp and the clinic website; the office is in Jeffersonville, IN and serves the Louisville, KY metro across the river.
• Single location confirmed.
• Dr. Rafael F. Cruz, MD, CIME’s credentials, background, and board certification confirmed from the kentuckianamedicine.com About page and the Wedge of Health Freedom listing.
• Services confirmed from the website (regenmedky.com) services and weight loss pages, including medical weight loss with Phentermine, HCG, and Semaglutide.
• Staff name (Richell) confirmed from a Yelp review excerpt.
• Testimonial confirmed from Yelp.
• Note: the practice uses two domains (regenmedky.com and kentuckianamedicine.com) and Facebook has 471+ likes; confirm the preferred primary URL if needed.
• Note: the site states many therapies are experimental/off-label and not FDA-approved — this is disclosed on the practice’s own materials.
• Strong category fit: medical weight loss (Phentermine, HCG, Semaglutide, lipotropics) is a named, featured service; the clinic is listed under Weight Loss Centers on Yelp.