Updated: July 1, 2026

BionwoRx

BionwoRx is a functional and regenerative medicine clinic in Carmel, Indiana, led by nurse practitioner Annamarie Salyer, FNP-C. The practice focuses on root-cause healing, offering personalized hormone and metabolic programs, medical weight management, peptide therapy, regenerative treatments, EBO2 blood cleansing, and IV nutrient therapy for patients across the greater Indianapolis area.
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Clinic Profile

BionwoRx (bionworx.com) is a functional and regenerative medicine center serving Carmel, Indianapolis, Zionsville, Westfield, Noblesville, and Fishers, Indiana. Rather than simply managing symptoms, the clinic focuses on identifying and addressing the root causes of illness through advanced diagnostics, lifestyle optimization, and targeted therapies designed to restore balance across the body’s systems. BionwoRx also offers telehealth visits for Indiana and Florida residents.

Address: 11495 N Pennsylvania St, Suite 230, Carmel, IN 46032 Phone: (317) 797-9139 Hours: Monday–Thursday 8:00 a.m.–4:00 p.m.; Friday, Saturday & Sunday closed (telehealth online hours Monday–Thursday 10 a.m.–6 p.m.) Website: bionworx.com

Background and History

BionwoRx was established in 2020 as a comprehensive medical facility specializing in functional and regenerative medicine. The clinic was built around the belief that the body can heal itself when given the right support, combining evidence-based science with a holistic, patient-centered philosophy.

Located near U.S. 31 and 116th Street minutes from downtown Carmel, the practice offers both in-person and telehealth care, blending functional medicine (uncovering the source of chronic illness) with regenerative medicine (tissue repair and recovery). Its stated mission is to help patients restore balance, vitality, and long-term wellness — partnering with each patient to achieve lasting resilience.

Services and Programs

BionwoRx offers a comprehensive menu across weight management, hormones, and regenerative wellness.

Weight Management

  • Medical weight management programs (comprehensive approach for sustainable results)
  • Weight optimization support through peptide therapy
  • Nutrition counseling and supplements

Hormone Optimization

  • Hormone Replacement Therapy (HRT) to restore natural balance
  • Customized hormone and metabolic programs

Regenerative Medicine

  • Regenerative joint injections
  • VSEL (Very Small Embryonic-Like cell) therapy
  • PRP / PPT therapy
  • Hair rejuvenation

Detox & IV Therapies

  • EBO2 (blood cleansing/ozone) therapy for Lyme, mold, and metal toxicity concerns
  • IV nutrient therapy
  • Peptide therapy (anti-aging, recovery, weight optimization, immune, performance)

Additional

  • Advanced diagnostic testing (Bion Core)
  • Sexual wellness
  • Telehealth (Indiana and Florida residents)

Doctors and Medical Professionals

BionwoRx is led by an experienced nurse practitioner specializing in functional and regenerative medicine.

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Annamarie Salyer, FNP-C — Nurse Practitioner & Lead Provider

Annamarie “Anna” Salyer is a board-certified Family Nurse Practitioner who leads clinical care at BionwoRx, including its peptide therapy program. She takes a personalized approach that blends evidence-based science with advanced clinical insight, designing each treatment plan around the patient’s unique health story. In her words, she believes “the body can heal itself when given the right support,” focusing on uncovering root causes, restoring balance, and empowering patients with the tools their bodies need to repair, renew, and thrive. Patients frequently praise her by name for her thoroughness, in-depth discussions, honesty about costs, and genuine, patient-first care.

Clinical & Support Team

Anna is supported by a professional clinical and support staff who administer treatments such as EBO2, IV therapy, and regenerative injections in a clean, welcoming environment. Prospective patients can confirm the current provider roster and credentials directly with the clinic.

Reviews and Patient Feedback

BionwoRx has an excellent review presence, including a 5-star rating across 22 reviews on Birdeye and strong Google feedback. Patients consistently praise the clinic’s root-cause approach, the thoroughness and honesty of provider Anna Salyer, and real improvements from treatments like EBO2 detox and regenerative joint injections. Prospective patients are encouraged to check current ratings on Google and Birdeye for the latest feedback.

Testimonials and Quotes

The following testimonials are drawn from the clinic’s Google and Birdeye reviews:

“I had an amazing experience at BionwoRx in Carmel, Indiana… I received EBO2 detox therapy and the results have been incredible. I feel great! My brain fog has cleared, my energy levels are up, and my focus has noticeably improved.” — Google reviewer

“My experience with BionwoRx and Ann Marie has surpassed expectations. She is methodical and knowledgeable but more than anything she cares about the value I’m getting as a patient… she does the right thing.” — Birdeye reviewer

“I had been struggling with plantar fasciitis for quite a while, and nothing seemed to give me lasting relief. After receiving a regenerative injection treatment from Anna, my foot pain started improving, and now, 9 months later, I’m still feeling great!” — Birdeye reviewer

Pricing and Value Signals

BionwoRx begins every program with a comprehensive consultation and personalized assessment, and offers online booking. Patients note the clinic’s transparency about costs and its patient-first, no-upsell approach. The practice provides both in-person and telehealth care for added convenience. Specific treatment pricing is provided during consultation.

Verification Notes

  • Address (11495 N Pennsylvania St, Suite 230, Carmel, IN 46032), phone (317) 797-9139, and hours confirmed from the clinic website and Yelp.
  • Note: a Birdeye listing shows a different/older address (600 E Carmel Dr, Suite 111/164) — the current website and Yelp list 11495 N Pennsylvania St, Suite 230; confirm the active address before publishing.
  • Establishment year (2020) confirmed from the Yelp business description.
  • Lead provider Annamarie “Anna” Salyer, FNP-C confirmed from the website peptide therapy page and multiple patient reviews. She is the primary named provider; confirm any additional providers/supervising physician with the clinic.
  • Services confirmed from the website navigation (weight management, HRT, peptide therapy, regenerative medicine, VSEL, EBO2, IV therapy) and Yelp.
  • Testimonials confirmed from Google (republished on the site) and Birdeye; review rating (5 stars, 22 reviews) confirmed from Birdeye.
  • The clinic’s site includes standard disclaimers that regenerative therapies are not offered as a cure and that some statements have not been evaluated by the FDA — disclosed on their own materials.
  • Category fit: offers medical weight management and weight-optimization peptide therapy within a functional/regenerative medicine practice; listed under Weight Loss Centers on Yelp.
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  • Simple monthly plan
  • Transparent pricing
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BionwoRx Contacts

  • 11495 N Pennsylvania St Ste 230, Carmel, IN 46032, United States

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