Updated: June 30, 2026

MDLifespan

MDLifespan is a physician-led longevity and detoxification clinic headquartered in Chicago, Illinois, specializing in therapeutic plasma exchange (TPE) through its patent-pending PlasmaXchange protocol, alongside biomarker testing, IV nutrient therapy, and regenerative treatments.
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Clinic Profile

MDLifespan (mdlifespan.com) operates its flagship clinic at 2400 N Ashland Avenue, Suite 250, Chicago, Illinois. The practice is the first physician-led medical group in the United States focused specifically on therapeutic plasma exchange for wellness and regenerative detoxification, and it is structured as a Public Benefit Corporation. Most consultations can be conducted virtually nationwide, while certain procedures are performed on-site at the Chicago location.

The clinic does not participate with insurance companies; services are offered on a self-pay basis through individual procedures or fully customized programs.

Address: 2400 N Ashland Avenue, Suite 250, Chicago, IL 60614 Phone: (844) 752-7629 Website: mdlifespan.com Insurance: Does not participate with insurance (self-pay)

Background and History

MDLifespan was founded by Dr. Paul Savage, who launched the company in 2022. After selling his prior age-management practice and briefly retiring to Brazil, Dr. Savage returned to medicine after a double-blind, placebo-controlled study on therapeutic plasma exchange’s potential to slow aging processes renewed his interest in the field. He built MDLifespan around the idea that health optimization depends less on what is added to the body than on what is removed from it.

The clinic developed the PlasmaXchange protocol — described by the founder as an “oil change for humans” — by reimagining therapeutic plasma exchange, a procedure used in clinical medicine for roughly 50 years, for modern detoxification and wellness use cases. Across 2023 and 2024, MDLifespan reported performing more than 300 TPE procedures combined with proprietary IV nutrient therapy, daily supplement powders, and regenerative therapies. The company is now expanding nationwide through a select network of provider locations, with the Chicago headquarters as its flagship.

Services and Programs

MDLifespan organizes its care around the PlasmaXchange protocol and a set of targeted programs and diagnostic panels.

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Therapeutic Plasma Exchange (PlasmaXchange Protocol)

  • Hospital-grade therapeutic plasma exchange (TPE)
  • Targeted protocols including MDL Brain (cognitive health), MDL Heart (cardiovascular and inflammation), MDL Immunity (immune resilience), MDL Longevity (anti-aging), MDL Toxin (comprehensive detox), MDL Baby (pre-pregnancy detox), and MDL Cancer (inflammation reduction)

Diagnostics and Testing

  • Biomarker and toxin testing panels (aging, cancer, heart, hormone, immune, microplastics, neurotransmitter, gut, and toxin panels)

Supportive and Regenerative Therapies

  • IV nutrient therapy (proprietary blend)
  • Daily supplement powder
  • Regenerative therapies
  • Physician consultations (available virtually and on-site)

Doctors and Medical Professionals

The MDLifespan Chicago team brings together physicians and specialists across longevity medicine, sports medicine, nutrition, and wellness coaching. The following roles are listed on the clinic’s official Chicago location page:

Dr. Paul Savage — Founder, CEO, and Chief Medical Officer

PlasmaXchange Protocol Creator and Precision Medicine Physician. Dr. Savage earned his Doctorate of Medicine from the University of Michigan Medical School and completed a residency in Emergency Medicine at the Detroit Medical Center (Grace & Mount Carmel Hospital, Detroit, MI). He holds a Fellowship in Metabolic Medicine from George Washington University and a Fellowship in Stem Cell Therapy from the University of South Florida, along with a Bachelor of Science in Mathematics from Michigan State University. He carries the credentials FACEP and FAARM and brings over 35 years of medical experience. Earlier in his career he founded BodyLogicMD, a national network of hormone therapy clinics.

Dr. Moises Irizarry-Roman

Specialist in Sports Medicine and Stem Cell Therapy.

Dr. Peter Schulz

Chiropractor and Medical Advisor.

Dr. Nikol Hopkins

Naprapath, Nutritionist, and Weight Loss Expert.

Dr. Gertrude Lyons

Life Coach.

Joey Thurman

Virtual Fitness Trainer.

This multidisciplinary structure lets the clinic pair its core plasma exchange and detoxification work with movement, nutrition, and behavioral support, addressing health optimization from several angles rather than through a single intervention.

Reviews and Patient Feedback

Public review data for MDLifespan as a clinic is currently limited, reflecting its status as a relatively young practice founded in 2022. Founder Dr. Paul Savage maintains a longer review history under his own name from his decades of prior practice. On Healthgrades, patient feedback for Dr. Savage is mixed, with a likelihood-of-recommending score of approximately 3.3 out of 5 — some patients describe him as among the best physicians they have seen, while others have left critical feedback. Prospective patients are encouraged to review current ratings directly and to call the clinic for the most up-to-date information.

Testimonials and Quotes

No verifiable patient testimonials specific to the MDLifespan clinic were publicly available at time of writing. Prospective patients can request current patient outcomes and references directly from the clinic.

Pricing and Value Signals

MDLifespan does not participate with insurance; all services are self-pay. The clinic offers both individual procedures and fully customized longevity programs, and provides free physician consultations for patients and practitioners interested in evaluating their toxic burden and identifying an appropriate protocol. Specific procedure pricing is provided directly by the clinic during consultation.

Verification Notes

  • Address (2400 N Ashland Avenue, Suite 250, Chicago, IL 60614) confirmed from the MDLifespan locations page and Chicago location page.
  • Phone (844) 752-7629 confirmed from the MDLifespan Chicago location page.
  • Provider names and roles (Dr. Paul Savage, Dr. Moises Irizarry-Roman, Dr. Peter Schulz, Dr. Nikol Hopkins, Dr. Gertrude Lyons, Joey Thurman) confirmed from the official Chicago location page (mdlifespan.com/location/mdlifespan/).
  • Dr. Savage’s credentials, fellowships, and education confirmed from the MDLifespan leadership page (mdlifespan.com/leadership/paul-savage-md/).
  • Founding year (2022), PBC status, “oil change for humans” framing, and 300+ TPE procedures (2023–2024) confirmed from the MDLifespan “Our Story” page.
  • Self-pay / no insurance participation confirmed from FindaTopDoc listing for Dr. Savage.
  • Healthgrades likelihood-to-recommend (~3.3/5) and mixed patient feedback confirmed from Dr. Savage’s Healthgrades profile.
  • PlasmaXchange protocols and diagnostic panels confirmed from the MDLifespan homepage and Chicago location navigation.
  • Note: MDLifespan is a longevity/plasma-exchange and detox practice rather than a traditional bariatric/weight-loss clinic; Dr. Nikol Hopkins is listed as a weight-loss expert, but the clinic’s core service is TPE/detox. Confirm category fit for BariatricReports.org before publishing.
  • Hours of operation were not publicly listed on the clinic site at time of writing; confirm with the clinic.
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MDLifespan Contacts

  • 770 N Halsted St Ste 204, Chicago, IL 60642, United States

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